Pepper Therapeutics
Pancreatic cancer is one of the deadliest cancers worldwide, with approximately 466,000 deaths each year. In Europe, around 132,000 people die annually from the disease, including about 3,150 in the Netherlands. Existing treatments still offer limited survival prospects. Only 5% of patients with pancreatic cancer survive five years after diagnosis. Pepper Therapeutics sees potential in […]
Flowsure
Flowsure automates urine output monitoring in hospitalized patients with catheters. By combining a low-cost, reusable hardware device with integrated software, Flowsure eliminates the need for manual measurements and data entry, improving nursing efficiency and ensuring real-time, accurate data flow into the Electronic Health Record (EHR). This enables earlier detection of complications like sepsis or hemorrhagic […]
Amplio Pharma
Amplio Pharma’s proprietary NovoBio Med technology amplifies the efficacy of methotrexate (MTX), the first line, cornerstone drug used to treat a wide variety of autoimmune diseases. NovoBioMed is able to trap MTX at its target, resulting in a faster response and better efficacy at a lower dose.
Arthrogen
Developing local gene therapy for chronic diseases, Arthrogen utilizes viral-mediated gene transfer to treat conditions like rheumatoid arthritis. Their approach focuses on intra-articular delivery of therapeutic genes for sustained local treatment with minimal systemic side effects. Using adeno-associated virus (AAV) vectors, they are developing and validating new vectors and therapeutic genes.
uniQure
Pioneering gene therapy, uniQure develops transformative treatments using its AAV-based technology platform. They achieved a landmark approval for their hemophilia B gene therapy, marking a significant advancement in genomic medicine. Building on this success, uniQure is advancing clinical programs for Huntington’s disease and developing a pipeline of preclinical candidates. Orignally spunout as Amsterdam Molecular Therapeutics […]
DCPrime
Pioneering cancer vaccines, DCPrime leverages its DCOne® dendritic cell technology to develop innovative immunotherapies. Their lead candidate, DCP-001, is currently in a Phase 2 study for Acute Myeloid Leukemia (AML), building on promising Phase 1 results. With Orphan Medicinal Product designation in the EU, DCPrime aims to provide effective treatments for hematological cancers, including Multiple […]
Quantib
Quantib focuses on improving patient care by bringing AI radiology solutions into clinical practice. Started in 2012 as a spin-out from Erasmus MC, University Medical Center Rotterdam, Quantib now has AI partnerships with the three largest academic hospitals in the Netherlands and with hospitals and private providers internationally.
Hipper Therapeutics
Hipper focuses on improving recovery after hip fractures in elderly patients (80+) – with a value proposition around early discharge from care centers and improved rehabilitation outcome.After a patient has fallen they are often worried about falling again and may lack confidence. This reduces activity levels which impacts rehabilitation and can lead to a downward […]
TrianecT
TrianecT develops StrokePointer, a portable EEG device that detects stroke severity in ambulances. The technology combines brain activity measurement through a proprietary headset with AI to diagnose Large Vessel Occlusion (LVO) strokes. Detection of an LVO stroke in the ambulance will allow patients to be immediately transported to a stroke center for timely treatment, to […]
Skyline Dx
Skyline Dx is a molecular diagnostics company focusing on oncology and infectious diseases. Their platform-agnostic tests range from PCR to Next Generation Sequencing technologies. Skyline Dx partners with discovery and commercial companies to develop and distribute their diagnostic tests. The company is dedicated to advancing precision medicine through innovative molecular diagnostics.