Arthrogen
Developing local gene therapy for chronic diseases, Arthrogen utilizes viral-mediated gene transfer to treat conditions like rheumatoid arthritis. Their approach focuses on intra-articular delivery of therapeutic genes for sustained local treatment with minimal systemic side effects. Using adeno-associated virus (AAV) vectors, they are developing and validating new vectors and therapeutic genes, with plans to move […]
uniQure
Pioneering gene therapy, uniQure develops transformative treatments using its AAV-based technology platform. They achieved a landmark approval for their hemophilia B gene therapy, marking a significant advancement in genomic medicine. Building on this success, uniQure is advancing clinical programs for Huntington’s disease and developing a pipeline of preclinical candidates. Orignally spunout as Amsterdam Molecular Therapeutics […]
DCPrime
Pioneering cancer vaccines, DCPrime leverages its DCOne® dendritic cell technology to develop innovative immunotherapies. Their lead candidate, DCP-001, is currently in a Phase 2 study for Acute Myeloid Leukemia (AML), building on promising Phase 1 results. With Orphan Medicinal Product designation in the EU, DCPrime aims to provide effective treatments for hematological cancers, including Multiple […]
Quantib
Quantib focuses on improving patient care by bringing AI radiology solutions into clinical practice. Started in 2012 as a spin-out from Erasmus MC, University Medical Center Rotterdam, Quantib now has AI partnerships with the three largest academic hospitals in the Netherlands and with hospitals and private providers internationally.
Hipper Therapeutics
Hipper is a B2B company that focuses on improving recovery after hip fractures in elderly patients (80+) – with a value proposition around early discharge from care centres and improved rehabilitation outcome. The revalidation centres (the customer) is the entity that covers the cost. Put simply after a patient has fallen they are worried about […]
TrianecT
TrianecT develops StrokePointer, a portable EEG device that detects stroke severity in ambulances. The technology combines brain activity measurement through a proprietary headset with AI to diagnose Large Vessel Occlusion (LVO) strokes. Detection of an LVO stroke in the ambulance will allow patients to be immediately transported to a stroke center for timely treatment, to […]
Skyline Dx
Skyline Dx is a molecular diagnostics company focusing on oncology and infectious diseases. Their platform-agnostic tests range from PCR to Next Generation Sequencing technologies. Skyline Dx partners with discovery and commercial companies to develop and distribute their diagnostic tests. The company is dedicated to advancing precision medicine through innovative molecular diagnostics.
SigmaSreening
SigmaScreening has developed a mammography device that reduces pain and improves diagnostic accuracy. Founded by Amsterdam UMC professors, the company aims to enhance breast cancer detection with their patented technology. SigmaScreening has licensed their technology to Teledyne, who continue development of the device.
Rsouth Antibodies
Rsouth Antibodies has developed a therapeutic antibody for Respiratory Syncytial Virus (RSV) that has been licensed to MedImmune (now AstraZeneca). AstraZeneca has finalized clinical validation and obtained regulatory approval for this antibody that is now marketed by Sanofi as Nirsevimab for prevention of RSV in infants. Since RSV infection have been on the rise again […]
PrimaGen
PrimaGen Holding focuses on developing molecular diagnostic tests and investing in bio- and medtech startups. The company generates revenues through the licensing of their diagnostics technology. PrimaGen Holding’s portfolio includes investments in PulseCath and Akkolens International.
